Genesis 15:18
15:18 That day the Lord made a covenant with Abram: “To your descendants I give this land, from the river of Egypt to the great river, the Euphrates River –
Deuteronomy 1:7
1:7 Get up now, resume your journey, heading for the Amorite hill country, to all its areas including the arid country, the highlands, the Shephelah, the Negev, and the coastal plain – all of Canaan and Lebanon as far as the Great River, that is, the Euphrates.
Deuteronomy 11:24
11:24 Every place you set your foot will be yours; your border will extend from the desert to Lebanon and from the River (that is, the Euphrates) as far as the Mediterranean Sea.
Revelation 9:14
9:14 saying to the sixth angel, the one holding the trumpet, “Set free the four angels who are bound at the great river Euphrates!”