Genesis 6:2

6:2 the sons of God saw that the daughters of humankind were beautiful. Thus they took wives for themselves from any they chose.

Genesis 27:46--28:2

27:46 Then Rebekah said to Isaac, “I am deeply depressed because of these daughters of Heth. If Jacob were to marry one of these daughters of Heth who live in this land, I would want to die!”

28:1 So Isaac called for Jacob and blessed him. Then he commanded him, “You must not marry a Canaanite woman! 28:2 Leave immediately for Paddan Aram! Go to the house of Bethuel, your mother’s father, and find yourself a wife there, among the daughters of Laban, your mother’s brother.

Genesis 28:8

28:8 Then Esau realized that the Canaanite women were displeasing to his father Isaac.