Also see definition of "Issue" in Word Study
Issue
ISSUE [isbe]
ISSUE - ish'-u:(1) (moledheth, tse'etsa'im; sperma, "seed"): Offspring, descendants (Gen 48:6; Isa 22:24; Mt 22:25 the King James Version).
(2) (zirmah; yatsa' (verb); rhusis): A gushing of fluid (semen, Ezek 23:20; water, 47:8; blood, Lk 8:43). See next article.
Also see definition of "Issue" in Word Study